Britain: Born first baby from mother with transplanted uterus

A little girl born in 27 February 2025 is the first baby born in Britain by mother, which had undergone transplantation uterine.

His 36 -year -old mother, Grace Davidsonsuffers from rare syndrome Mayer-Rokitansky-Küster-Hauser (Mrkh). Because of him he was born without a functional uterus, so in 2023 he proceeded with the transplant. At that time he was the only successful in Britain.

Donor of the graft was her sister, Amywho had completed her family and did not want to have other children.

Amy, who was named her aunt, was born two years after the pioneering transplant. When Grace held her in her hands for the first time she was something “unique” and “unreal,” she told the BBC.

“It was shocking because by then we had never imagined what it would be like to have it in our lives,” she said, referring to her husband, Angus. “It was real wonderful.”

Happy parents hope to have a second child with the help of the transplanted uterus.

Grace will be re -operated to remove and stop taking immunosuppressive drugs. They are given to her so that her body does not reject the graft.

65 babies were born

MRKH syndrome is a disorder mainly of the female genital system. It is estimated that it affects 1 in 4,500 girls, who are born without or with an incompletely developed uterus (uterine aplasia). They may also have an incompletely developed or absent vagina. However, their external genitals are normal.

Uterine transplantation is a relatively new treatment for those who wish to have children. The first successful became the 2014 in Sweden.

Since then, they have been executed approximately 135 analogous transplants In more than 10 countries around the world. These include the US, France, Germany, India and Britain.

Of the women who have been transplanted, 65 babies have been born so far. Amy was born with a scheduled Caesarean section at the Queen Charlotte’s and Chelsea Hospital in London.

The uterine transplantation on her mother had been done just two years earlier in February 2023. She had lasted 17 hours and had participated in more than 30 doctors, nurses and other health staff.

The transplant was carried out as part of a clinical trial in the hospital, which would include a total of 15 women. So far, 10 patients have freezed embryos or undergoing fertility therapy, prepared for their transplantation.

According to the study protocol, five of the transplants will be made by live donors (as in the case of Grace). The other ten will be made by a deceitful donors. So far, three transplants have been carried out by bargain donors. However, other details have not been made public because families and torture should consent.

Source: iatropedia.gr

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