How do vaccines work in real time? This question is answered by a study conducted in the USA and revealed important data about vaccines of Pfizer, Moderna, Johnson & Johnson.
The effectiveness of medications, such as vaccines, may actually differ from that seen in clinical trials. This may be due to the fact that sometimes pharmacological interventions are performed in well-controlled conditions within clinical trials but do not respond to real conditions of daily clinical practice. For this reason, studies of the effectiveness of vaccines in the context of daily clinical practice are extremely important.
A recent US study published in the New England Journal of Medicine shows the high efficacy of Pfizer, Moderna and Johnson & Johnson vaccines in real life in people over 50 years of age.
The professors of the Medical School of the National and Kapodistrian University of Athens, Gikas Majorkinis and Thanos Dimopoulos (Rector of EKPA) summarize the main findings of the study. After analyzing data from approximately 100,000 hospital admissions between January 1 and June 22, 2021, the researchers found that, in real conditions, the effectiveness of vaccines in protecting against hospital admission, emergency visit or intensive care unit is close to 90%.
An interesting fact that this study showed is that the adequacy of the immune response increases significantly after 13the day from the first dose and is maximized around 50 days from the first dose so it seems that remains stable for at least 3 months after the first dose.
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